Congrats to Emilia, Ang, Xuemeng, Tanner and Elisabeth on their paper in Nature Communications studying RNA 5-methylcytidine dioxygenase enzymes!
TRIBE-ID preprint posted
We developed a method to study dynamic RNA-protein interactions using rapamycin-induced dimerization and RNA A:I editing. Read about it on bioRxiv, and congrats to Josh!
Emilia graduates!
Congratulations to Dr. Arguello, who is the first PhD student to graduate from the Kleiner lab! We wish her well in the future and are grateful for all of her contributions to the group.
Kleiner lab outreach
As part of lab outreach and funded through the NSF, we have assembled 2 primer videos on key discoveries in molecular biology/nucleic acid chemistry. The videos can be found on the Outreach section of the lab website. A nice write up of our efforts can be found on the Department and University websites.
RNA imaging pre-print posted on bioRxiv
A manuscript describing our collaboration with the Purse lab (SDSU) to develop fluorescent nucleosides for RNA metabolic labeling and imaging is posted on bioRxiv. Congrats to Danyang, Emilia and all! Read about it here.
5-formylcytosine sequencing paper publis...
Our paper using malononitrile to sequence 5-formylcytosine (f5C) modifications on RNA is published in ACS Chemical Biology! Congratulations to Ang, Xuemeng, and Emilia!
RNA metabolic labeling review published
Our review on metabolic labeling of RNA with modified ribonucleosides is published in Molecular Omics. Check it out here!
RNABPP paper published in Nature Chemica...
Our paper describing RNA-mediated activity-based protein profiling (RNABPP) is published in Nature Chemical Biology. Congratulations to Crystal, Ang and Nathan!
Muhan joins the lab!
Our collaborative paper on m6A readers i...
Our joint effort with the Laie lab describing m6A readers in Drosophila is published in Nature Communicationsl