Our collaborative work with the Purse lab (SDSU) using metabolically incorporated fluorescent nucleosides for live-cell RNA imaging is published in JACS! Congratulations to Danyang, Emilia and the rest of the team!
Congrats to Emilia, Ang, Xuemeng, Tanner and Elisabeth on their paper in Nature Communications studying RNA 5-methylcytidine dioxygenase enzymes! Write-up on the Department website.
We developed a method to study dynamic RNA-protein interactions using rapamycin-induced dimerization and RNA A:I editing. Read about it on bioRxiv, and congrats to Josh!
Congratulations to Dr. Arguello, who is the first PhD student to graduate from the Kleiner lab! We wish her well in the future and are grateful for all of her contributions to the group.
As part of lab outreach and funded through the NSF, we have assembled 2 primer videos on key discoveries in molecular biology/nucleic acid chemistry. The videos can be found on the Outreach section of the lab website. A nice write up of our efforts can be found on the Department and University websites.
A manuscript describing our collaboration with the Purse lab (SDSU) to develop fluorescent nucleosides for RNA metabolic labeling and imaging is posted on bioRxiv. Congrats to Danyang, Emilia and all! Read about it here.
Our paper using malononitrile to sequence 5-formylcytosine (f5C) modifications on RNA is published in ACS Chemical Biology! Congratulations to Ang, Xuemeng, and Emilia!
Our review on metabolic labeling of RNA with modified ribonucleosides is published in Molecular Omics. Check it out here!
Our paper describing RNA-mediated activity-based protein profiling (RNABPP) is published in Nature Chemical Biology. Congratulations to Crystal, Ang and Nathan!