Princeton publications:

22. Mechanisms of Epitranscriptomic Gene Regulation.
Seo, K.W.; Kleiner, R.E. Biopolymers doi: 10.1002/bip.23403 (2020) web.

21. Cell- and Polymerase-Selective Metabolic Labeling of Cellular RNA with 2′-Azidocytidine.
Wang, D.; Zhang, Y.; Kleiner, R.E. J. Am. Chem. Soc. 142, 14417-14421 (2020) web.

20. YTHDF2 recognition of N1-methyladenosine (m1A)-modified RNA is associated with transcript destabilization.

Seo, K. W.; Kleiner, R. E. ACS Chem. Biol. (2020), 15(1): 132-139 web.

19. High-throughput approaches to profile RNA-protein interactions.
Nechay, M.; Kleiner, R. E. Curr. Opin. Chem. Biol. (2019), 54:37-44 web.

18. In Vitro Selection with a Site-Specifically Modified RNA Library Reveals the Binding Preferences of N6-Methyladenosine Reader Proteins.
Arguello, A. E.; Leach, R. W.; Kleiner, R. E. Biochemistry (2019), 58(31):3386-3395 web.

17. A Metabolic Engineering Approach to Incorporate Modified Pyrimidine Nucleosides into Cellular RNA.
Zhang, Y.; Kleiner, R.E. J. Am. Chem. Soc. (2019), 141(8):3347-3351 web.

16. A Photocrosslinking-Based RNA Chemical Proteomics Approach to Profile m6 A-Regulated Protein-RNA Interactions.
Arguello, A.E.; Srikumar, T; Kleiner, R.E. Curr. Protoc. Nucleic Acid Chem. (2018), 75(1) web.

15. RNA Chemical Proteomics Reveals the N6-Methyladenosine (m6A)-Regulated Protein-RNA Interactome. 
Arguello, A. E.; DeLiberto, A. N.; Kleiner, R. E.¬†J. Am. Chem. Soc. (2017),¬†139¬†(48), pp 17249‚Äď17252¬†web.

JACS Spotlight: Photo-cross-linking Finds Partners of a Widespread RNA Modification

14. Reading the RNA Code
Kleiner, R. E.¬†Biochemistry¬†(2017),¬†57¬†(1), pp 11‚Äď12¬†web

PhD and Postdoc publications:

13. A Chemical Proteomics Approach to Reveal Direct Protein-Protein Interactions in Living Cells 
Kleiner, R. E.; Hang, L. E.; Molloy, K. R.; Chait, B. T.; Kapoor, T. M. Cell Chem. Biol. (2017) 25 (1), 110-120.e3. web.

12. Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles 
Aleem, S. U.*; Georghiou, G.*; Kleiner, R. E.*; Guja, K. E.; Craddock, B. P.; Lyczek, A.; Chan, A. I.; Garcia-Diaz, M.; Miller, W. T.; Liu, D. R.; Seeliger, M. A. Cell Chem. Biol. 23, 1103-1112 (2016).

11. Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends
Ti, S. C.; Pamula, M. C.; Howes, S. C.; Duellberg, C.; Cade, N. I.; Kleiner, R. E.; Forth, S.; Surrey, T.; Nogales, E.; Kapoor, T. M. Cell 4, 72-84 (2016).

10. Chemical Proteomics Reveals a ő≥H2AX-53BP1 Interaction in the DNA Damage Response
Kleiner, R. E.; Verma, P.; Molloy, K. R.; Chait, B. T.; Kapoor, T. M. Nat. Chem. Biol. 10, 807-814 (2015).

9. Anti-Diabetic Activity of Insulin-Degrading Enzyme Inhibitors Mediated by Multiple Hormones
Maianti, J. P.; McFedries, A.; Foda, Z. H.; Kleiner, R. E.; Du, X.; Lessring, M.; Tang, W.; Charron, M. J.; Seeliger, M. A.; Saghatelian, A.; Liu, D. R. Nature 511, 94-98 (2014).

8. Bumping Up Kinase Activity with an ATP-Derived Neo-Substrate
Kleiner, R. E.; Kapoor, T. M. Cell 154, 716-718 (2013).

7. Site-Specific Chemistry on the Microtubule Polymer 
Kleiner, R. E.; Ti, S. C.; Kapoor, T. M. J. Am. Chem. Soc. 135, 12520-12523 (2013).

6. Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocycles 
Georghiou, G.*; Kleiner, R. E.*; Pulkoski-Gross, M.; Liu, D. R.; Seeliger, M. A. Nat. Chem. Biol. 8, 366-374 (2012).

5. Small-Molecule Discovery from DNA-Encoded Chemical Libraries 
Kleiner, R. E.*; Dumelin, C. E.*; Liu, D. R. Chem. Soc. Rev. 40, 5707-5717 (2011).

4. In Vitro Selection of a DNA-Templated Small-Molecule Library Reveals a Class of Macrocyclic Kinase Inhibitors 
Kleiner, R. E.; Dumelin, C. E.; Tiu, G. C.; Sakurai, K.; Liu, D. R. J. Am. Chem. Soc. 132, 11779-11791 (2010).

3. An In Vitro Translation, Selection and Amplification System for Peptide Nucleic Acid
Brudno, Y.; Birnbaum, M. E.; Kleiner, R. E.; Liu, D. R. Nat. Chem. Biol. 6, 148-155 (2010).

2. DNA-Templated Polymerization of Side-Chain-Functionalized Peptide Nucleic Acid Aldehydes 
Kleiner, R. E.; Brudno, Y.; Birnbaum, M. E.; Liu, D. R. J. Am. Chem. Soc. 130, 4646-4659 (2008).

1. An Intein-Based Genetic Selection Enables Construction of a High-Quality Library of Binary Patterned De Novo Sequences
Bradley, L. H.; Kleiner, R. E.; Wang, A. F.; Hecht, M. H.; Wood, D.W. Protein Eng. Des. Sel. 18, 201-207 (2005).